Joe Murphy was sent off on his 250th league start as Blackpool turned around a one-goal deficit to beat Scunthorpe 4-1 and maintain their unbeaten home record.
The Iron were comfortably the better side for an hour and took the lead through Paul Hayes' 51st-minute opener, before Ian Evatt levelled for the home side.
Keeper Murphy was then sent off for deliberate handball, with the decision paving the way for Charlie Adam, Ben Burgess and Alex Baptiste to seal the win for Ian Holloway's men, leaving Scunthorpe without a win at Bloomfield Road since April 2000.
Hayes gave his side a deserved lead when he clipped home, but the Iron were only ahead for nine minutes before Evatt nodded home.
Murphy walked after saved Baptiste's effort outside the area and Adam slammed the resulting kick home.
The the hosts ran riot as Burgess converted from close range and Baptiste scored with a fine 25-yard effort.